MOTS-c is A 16-amino-acid peptide encoded in the mitochondrial genome. All ThePeptideCode products are laboratory research use only.

Mechanism & background

MOTS-c (“Mitochondrial Open Reading Frame of the 12S rRNA-c”) is one of a handful of known mitochondrial-derived peptides. Research has linked it to AMPK pathway activation, glucose handling in skeletal-muscle cell lines, and exercise-related metabolic endpoints.

Common research applications

Mitochondrial-biology research, metabolic-pathway studies, exercise-physiology models, longevity research.

Reconstitution and storage

MOTS-c ships as a lyophilised powder in a sealed glass vial. Reconstitute with bacteriostatic water following the step-by-step reconstitution guide. Once reconstituted, store at 2–8 °C for short-term use, or aliquot and freeze at −20 °C for longer storage. See the full dosage and storage guide.

Purity and batch verification

Every MOTS-c batch shipped by ThePeptideCode is verified by an ISO 17025-accredited independent laboratory using HPLC (purity) and mass spectrometry (identity). Typical purity is ≥99%. Look up your batch ID on the verification page.

Buy MOTS-c for research in the UK

UK Express £6.99 (1–2 working days), free over £100. EU £14.99. MOTS-c 10 mg.