Semaglutide is A long-acting GLP-1 receptor agonist research peptide. All ThePeptideCode products are laboratory research use only.

Mechanism & background

Semaglutide is a 31-amino-acid peptide based on the native GLP-1 sequence with two key modifications — an Aib substitution at position 8 (resistance to DPP-4 cleavage) and a C18 fatty-diacid spacer (albumin binding). These give a half-life of around 7 days in research subjects.

Common research applications

GLP-1 pathway research, comparative dual-agonist studies (versus tirzepatide), weight and glucose research models.

Reconstitution and storage

Semaglutide ships as a lyophilised powder in a sealed glass vial. Reconstitute with bacteriostatic water following the step-by-step reconstitution guide. Once reconstituted, store at 2–8 °C for short-term use, or aliquot and freeze at −20 °C for longer storage. See the full dosage and storage guide.

Purity and batch verification

Every Semaglutide batch shipped by ThePeptideCode is verified by an ISO 17025-accredited independent laboratory using HPLC (purity) and mass spectrometry (identity). Typical purity is ≥99%. Look up your batch ID on the verification page.

Buy Semaglutide for research in the UK

UK Express £6.99 (1–2 working days), free over £100. EU £14.99. See related products.